Hs00332882_cn

• Gene Symbol: PDK4
• Assay Reference Genome Location: Chr.7:95585480 on build GRCh38
• Cytoband: 7q21.3

Target Gene Details

• Entrez Gene ID: 5166
• Gene Name: pyruvate dehydrogenase kinase 4
• Gene Aliases: -
• Location: Chr.7:95583497-95596613 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDK4	NM_002612.3	11	1717	NP_002603.1
	AK096428.1	12	1516
	AK098151.1	7	1031
	AK223328.1			BAD97048.1
	BC040239.1	11	1597	AAH40239.1
	U54617.1	11	1619	AAC50669.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1023193	Chr.7:93602376 - 95828660 on Build GRCh38	Gain	PON1 LOC105375405 CASD1 PDK4 LOC105375401 PEG10 SGCE MIR4652 PON2 GNGT1 PON3 PPP1R9A GNG11 ASB4 TFPI2 DYNC1I1 COL1A2 BET1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
glucose metabolic process
protein phosphorylation
regulation of pH
insulin receptor signaling pathway
cellular response to starvation
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of cellular ketone metabolic process
regulation of glucose metabolic process
regulation of fatty acid biosynthetic process
glucose homeostasis
response to starvation
regulation of bone resorption
regulation of fatty acid oxidation
cellular response to fatty acid
reactive oxygen species metabolic process
xenophagy
negative regulation of anoikis

Function(s)

protein kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
ATP binding