Hs00335077_cn

• Gene Symbol: EXOSC10
• Assay Reference Genome Location: Chr.1:11079757 on build GRCh38
• Cytoband: 1p36.22

Target Gene Details

• Entrez Gene ID: 5394
• Gene Name: exosome component 10
• Gene Aliases: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
• Location: Chr.1:11066613-11099910 on Build GRCh38
• Assay Gene Location: Overlaps Intron 13 - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOSC10	NM_001001998.2			NP_001001998.1
	NM_002685.3			NP_002676.1
	XM_005263475.2			XP_005263532.2
	XM_017001494.1			XP_016856983.1
	XM_017001495.1			XP_016856984.1
	XM_017001496.1			XP_016856985.1
	XM_017001497.1			XP_016856986.1
	AB209236.1	12	2745	BAD92473.1
	AK123365.1
	AK296559.1
	BC009908.2			AAH09908.2
	BC039901.1			AAH39901.1
	BC073788.1			AAH73788.1
	L01457.1			AAB59352.1
	X66113.1			CAA46904.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv545407	Chr.1:11000018 - 11377969 on Build GRCh38	Gain	MTOR-AS1 UBIAD1 LOC105376736 ANGPTL7 MTOR SRM EXOSC10 MASP2 TARDBP

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
maturation of 5.8S rRNA
nuclear-transcribed mRNA catabolic process
rRNA processing
dosage compensation by inactivation of X chromosome
nuclear mRNA surveillance
CUT catabolic process
nuclear polyadenylation-dependent rRNA catabolic process
histone mRNA catabolic process
nuclear retention of unspliced pre-mRNA at the site of transcription
RNA phosphodiester bond hydrolysis, exonucleolytic

Function(s)

nucleotide binding
3'-5'-exoribonuclease activity
exoribonuclease activity
protein binding
poly(A) RNA binding