Hs00361522_cn

• Gene Symbol: XRCC2
• Assay Reference Genome Location: Chr.7:152676048 on build GRCh38
• Cytoband: 7q36.1

Target Gene Details

• Entrez Gene ID: 7516
• Gene Name: X-ray repair cross complementing 2
• Gene Aliases: FANCU
• Location: Chr.7:152646498-152676165 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
XRCC2	NM_005431.1			NP_005422.1
	AF035587.1			AAC05369.1
	AK313607.1
	BC042137.1			AAH42137.1
	Y08837.1			CAA70065.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1017565	Chr.7:152450845 - 152758187 on Build GRCh38	Gain	XRCC2 LINC01003
nsv831193	Chr.7:152656459 - 152895593 on Build GRCh38	Loss	XRCC2 ACTR3B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mitotic cell cycle
meiotic DNA recombinase assembly
double-strand break repair via homologous recombination
DNA synthesis involved in DNA repair
strand displacement
in utero embryonic development
somitogenesis
DNA repair
mitotic recombination
meiotic nuclear division
reciprocal meiotic recombination
response to X-ray
response to ionizing radiation
response to gamma radiation
multicellular organism growth
strand invasion
negative regulation of neuron apoptotic process
positive regulation of neurogenesis
centrosome organization
regulation of fibroblast apoptotic process

Function(s)

recombinase activity
four-way junction DNA binding
double-stranded DNA binding
single-stranded DNA binding
endodeoxyribonuclease activity
protein binding
ATP binding
DNA-dependent ATPase activity