Hs00374946_cn

• Gene Symbol: NELFB
• Assay Reference Genome Location: Chr.9:137263085 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 25920
• Gene Name: negative elongation factor complex member B
• Gene Aliases: COBRA1, NELF-B
• Location: Chr.9:137255300-137273548 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NELFB	NM_015456.4			NP_056271.3
	AF464935.1			AAL69965.1
	AK022651.1			BAB14157.1
	AK091056.1
	AL050280.1			CAB43381.3
	BC011892.1			AAH11892.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TOR4A RNF224 TUBB4B TPRN NDOR1 NELFB TMEM203 C9orf173-AS1 RNF208 STPG3 NRARP SLC34A3 SSNA1 CYSRT1 EXD3 FAM166A ANAPC2
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	TOR4A RNF224 STPG3 TUBB4B NRARP NELFB SLC34A3 CYSRT1 EXD3 C9orf173-AS1 FAM166A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TOR4A C9orf142 ENTPD2 NDOR1 CCDC183 NOXA1 MIR7114 ENTPD8 PRR31 C9orf139 PHPT1 EDF1 TRAF2 MIR3621 NRARP FAM166A ANAPC2 DPP7 RNF224 TPRN LCNL1 FUT7 MIR4479 MIR4292 SAPCD2 SSNA1 TMEM210 FBXW5 LOC101930307 UAP1L1 PTGDS TMEM203 GRIN1 CCDC183-AS1 C9orf172 NSMF CYSRT1 ABCA2 EXD3 PNPLA7 TUBB4B MAN1B1-AS1 NELFB RABL6 MAN1B1 C9orf173-AS1 CLIC3 RNF208 STPG3 LCN12 SLC34A3 NPDC1 C8G MAMDC4 LRRC26
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TOR4A RNF224 TUBB4B TPRN NDOR1 NELFB TMEM203 GRIN1 C9orf173-AS1 RNF208 STPG3 MIR3621 NRARP SLC34A3 SSNA1 TMEM210 CYSRT1 EXD3 FAM166A LRRC26 ANAPC2
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TOR4A RNF224 TUBB4B TPRN NDOR1 NOXA1 NELFB ENTPD8 TMEM203 GRIN1 C9orf173-AS1 RNF208 STPG3 MIR3621 NRARP SLC34A3 SSNA1 TMEM210 CYSRT1 EXD3 FAM166A LRRC26 ANAPC2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TOR4A MIR6722 C9orf142 ENTPD2 EGFL7 NDOR1 CCDC183 LCN10 SNORA17A PRR31 C9orf139 PHPT1 EDF1 TRAF2 MIR3621 NRARP LINC01451 FAM166A ANAPC2 DPP7 RNF224 TPRN LCNL1 FUT7 SNHG7 MIR126 MIR4479 MIR4292 SAPCD2 AGPAT2 SNORA17B SSNA1 TMEM210 FBXW5 LOC101930307 UAP1L1 PTGDS LCN8 TMEM203 GRIN1 TMEM141 FAM69B LCN6 CCDC183-AS1 C9orf172 LCN15 CYSRT1 ABCA2 EXD3 HSPC324 TUBB4B MAN1B1-AS1 NELFB RABL6 MAN1B1 C9orf173-AS1 CLIC3 RNF208 STPG3 LOC100128593 LCN12 SLC34A3 NPDC1 C8G MAMDC4 LRRC26

More Information

Additional Information:

For this assay, SNP(s) [rs117427616] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
negative regulation of transcription elongation from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

protein binding