Hs00375126_cn

• Gene Symbol: MAP3K13
• Assay Reference Genome Location: Chr.3:185482618 on build GRCh38
• Cytoband: 3q27.2

Target Gene Details

• Entrez Gene ID: 9175
• Gene Name: mitogen-activated protein kinase kinase kinase 13
• Gene Aliases: LZK, MEKK13, MLK
• Location: Chr.3:185282938-185489094 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP3K13	NM_001242314.1	15	3354	NP_001229243.1
	NM_001242317.1	13	2618	NP_001229246.1
	NM_004721.4	14	3469	NP_004712.1
	XM_011513310.2	14	3627	XP_011511612.1
	XM_017007456.1	15	3365	XP_016862945.1
	XM_017007457.1	13	3067	XP_016862946.1
	XM_017007458.1	15	3255	XP_016862947.1
	XM_017007459.1	14	3194	XP_016862948.1
	AB001872.1	14	3335	BAA24817.1
	AK297646.1	13	2606
	AK302951.1	14	2831
	BC111726.1			AAI11727.1

Target Gene Details

• Entrez Gene ID: 90407
• Gene Name: transmembrane protein 41A
• Gene Aliases: 2900010K02Rik
• Location: Chr.3:185482671-185499057 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMEM41A

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829818	Chr.3:185411745 - 185567640 on Build GRCh38	Loss	LIPH MAP3K13 TMEM41A
esv3893837	Chr.3:185291669 - 185483550 on Build GRCh38	Gain	MAP3K13 TMEM41A

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity

Function(s)

protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
identical protein binding
protein homodimerization activity
metal ion binding