Hs00389172_cn

• Gene Symbol: ALKBH3
• Assay Reference Genome Location: Chr.11:43920168 on build GRCh38
• Cytoband: 11p11.2

Target Gene Details

• Entrez Gene ID: 221120
• Gene Name: alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
• Gene Aliases: ABH3, DEPC-1, DEPC1, PCA1, hABH3
• Location: Chr.11:43880807-43920275 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALKBH3	NM_139178.3	10	1462	NP_631917.1
	AB042029.1	10	1425	BAB70508.1
	AK125602.1	1	2521
	BC015155.1	5	748	AAH15155.1
	BC067257.1	10	1459	AAH67257.1
	CD364334.1	1	124
	U38442.1	1	76

Target Gene Details

• Entrez Gene ID: 100507300
• Gene Name: ALKBH3 antisense RNA 1
• Gene Aliases: -
• Location: Chr.11:43909289-43920944 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALKBH3-AS1	NR_038907.1
	AK097541.1
	BI827816.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv554171	Chr.11:43897861 - 43927961 on Build GRCh38	Gain	ACCSL ALKBH3-AS1 SEC14L1P1 ALKBH3
nsv832138	Chr.11:43778980 - 43966454 on Build GRCh38	Gain	ACCSL HSD17B12 ALKBH3-AS1 SEC14L1P1 ALKBH3 C11orf96

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

DNA repair
DNA dealkylation involved in DNA repair
cell proliferation
oxidative single-stranded DNA demethylation
oxidative single-stranded RNA demethylation

Function(s)

protein binding
ferrous iron binding
L-ascorbic acid binding
DNA-N1-methyladenine dioxygenase activity
cytosine C-5 DNA demethylase activity
RNA N1-methyladenosine dioxygenase activity