Hs00408691_cn

• Gene Symbol: SIPA1
• Assay Reference Genome Location: Chr.11:65641271 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 6494
• Gene Name: signal-induced proliferation-associated 1
• Gene Aliases: SPA1
• Location: Chr.11:65638107-65650930 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIPA1	NM_006747.3	2	517	NP_006738.3
	NM_153253.29	2	646	NP_694985.29
	XM_005274189.2	2	591	XP_005274246.1
	XM_011545214.1	2	557	XP_011543516.1
	AB005666.1	2	646	BAA22197.1
	AF029789.1	2	499	AAC32547.1
	AK303551.1	2	591
	AK308234.1	2	488
	AK310068.1	1	425
	BC010492.1	2	468	AAH10492.1
	BC110353.1	2	486	AAI10354.1
	DN999403.1	2	524

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1969n54	Chr.11:65568234 - 65663889 on Build GRCh38	Loss	SSSCA1-AS1 RELA MAP3K11 EHBP1L1 MIR4690 SIPA1 SSSCA1 FAM89B MIR4489 KCNK7 PCNX3
nsv951018	Chr.11:65525430 - 65662029 on Build GRCh38	Deletion	SSSCA1-AS1 RELA LTBP3 MIR4690 SIPA1 SSSCA1 MIR4489 MAP3K11 EHBP1L1 FAM89B SCYL1 KCNK7 PCNX3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

cytoskeleton organization
negative regulation of cell adhesion
signal transduction
cell proliferation
negative regulation of cell growth
intracellular signal transduction
cellular response to water deprivation
positive regulation of GTPase activity
negative regulation of cell cycle
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
protein C-terminus binding