Hs00422937_cn

• Gene Symbol: SEMA5B
• Assay Reference Genome Location: Chr.3:122909224 on build GRCh38
• Cytoband: 3q21.1

Target Gene Details

• Entrez Gene ID: 54437
• Gene Name: semaphorin 5B
• Gene Aliases: SEMAG, SemG
• Location: Chr.3:122909193-123028605 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA5B	NM_001031702.3			NP_001026872.2
	NM_001256346.1			NP_001243275.1
	NM_001256347.1			NP_001243276.1
	NM_001256348.1			NP_001243277.1
	NR_046079.1
	XM_017006638.1			XP_016862127.1
	AB040878.1
	AK001234.1			BAA91570.1
	AY358124.1			AAQ88491.1
	BC077726.1			AAH77726.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829706	Chr.3:122797072 - 122951740 on Build GRCh38	Gain	LOC100129550 DIRC2 SEMA5B

More Information

Additional Information:

For this assay, SNP(s) [rs80353916] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
positive regulation of cell migration
axon extension
negative regulation of axon extension involved in axon guidance
detection of light stimulus involved in visual perception
negative chemotaxis
semaphorin-plexin signaling pathway
neuron projection guidance

Function(s)

semaphorin receptor binding
chemorepellent activity