Hs00424808_cn

• Gene Symbol: PAICS
• Assay Reference Genome Location: Chr.4:56435822 on build GRCh38
• Cytoband: 4q12

Target Gene Details

• Entrez Gene ID: 10606
• Gene Name: phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase
• Gene Aliases: ADE2, ADE2H1, AIRC, PAIS
• Location: Chr.4:56435749-56461368 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PAICS	NM_006452.3	1	74	NP_006443.1
	AK294821.1	1	71
	BC010273.1	1	48	AAH10273.1
	CN337183.1	1	82

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1161086	Chr.4:56310907 - 56510457 on Build GRCh38	Duplication	ARL9 AASDH KIAA1211 LOC100506514 SRP72 PAICS PPAT
dgv5213n100	Chr.4:56076751 - 56538345 on Build GRCh38	Gain	THEGL LOC101928760 ARL9 AASDH KIAA1211 LOC100506514 SRP72 PAICS PPAT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

'de novo' IMP biosynthetic process
purine nucleobase biosynthetic process
purine ribonucleoside monophosphate biosynthetic process
adenine biosynthetic process
cell-cell adhesion

Function(s)

phosphoribosylaminoimidazole carboxylase activity
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
protein binding
ATP binding
identical protein binding
cadherin binding involved in cell-cell adhesion