Hs00430161_cn

• Gene Symbol: ADAM10
• Assay Reference Genome Location: Chr.15:58597246 on build GRCh38
• Cytoband: 15q21.3

Target Gene Details

• Entrez Gene ID: 102
• Gene Name: ADAM metallopeptidase domain 10
• Gene Aliases: AD10, AD18, CD156c, CDw156, HsT18717, MADM, RAK, kuz
• Location: Chr.15:58595204-58749978 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAM10	NM_001110.3	16	2992	NP_001101.1
	NM_001320570.1	15	2899	NP_001307499.1
	XM_017021861.1	17	3047	XP_016877350.1
	AF009615.1	16	3017	AAC51766.1
	AK023460.1	4	2252
	BC126253.1
	BX372217.2
	Z48579.1			CAA88463.1

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

in utero embryonic development
protein phosphorylation
membrane protein ectodomain proteolysis
negative regulation of cell adhesion
Notch signaling pathway
Notch receptor processing
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
positive regulation of T cell chemotaxis
protein processing
extracellular matrix disassembly
positive regulation of cell growth
positive regulation of cell migration
response to tumor necrosis factor
monocyte activation
ephrin receptor signaling pathway
PMA-inducible membrane protein ectodomain proteolysis
constitutive protein ectodomain proteolysis

Function(s)

endopeptidase activity
metalloendopeptidase activity
receptor binding
integrin binding
protein binding
metallopeptidase activity
zinc ion binding
SH3 domain binding
protein kinase binding
protein homodimerization activity