Hs00462384_cn

• Gene Symbol: CHRNB2
• Assay Reference Genome Location: Chr.1:154567846 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 1141
• Gene Name: cholinergic receptor nicotinic beta 2 subunit
• Gene Aliases: EFNL3, nAChRB2
• Location: Chr.1:154567781-154580026 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRNB2	NM_000748.2	1	66	NP_000739.1
	XM_017000180.1			XP_016855669.1
	U62437.1	1	66	AAB40115.1
	X53179.1			CAA37320.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv521887	Chr.1:154264094 - 154711630 on Build GRCh38	Gain	SHE TDRD10 ATP8B2 HAX1 LOC101928101 ADAR UBE2Q1-AS1 IL6R UBAP2L KCNN3 AQP10 UBE2Q1 CHRNB2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

action potential
conditioned taste aversion
response to hypoxia
ion transport
calcium ion transport
smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
visual perception
sensory perception of sound
learning
memory
locomotory behavior
associative learning
visual learning
regulation of dopamine secretion
sensory perception of pain
vestibulocochlear nerve development
optic nerve morphogenesis
lateral geniculate nucleus development
central nervous system projection neuron axonogenesis
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
response to nicotine
behavioral response to nicotine
social behavior
regulation of dopamine metabolic process
B cell activation
response to cocaine
regulation of circadian sleep/wake cycle, REM sleep
regulation of circadian sleep/wake cycle, non-REM sleep
response to ethanol
negative regulation of action potential
regulation of dendrite morphogenesis
neurological system process
cognition
protein heterooligomerization
membrane depolarization
regulation of synapse assembly
synaptic transmission involved in micturition
cation transmembrane transport

Function(s)

acetylcholine-activated cation-selective channel activity
protein binding
drug binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding
protein heterodimerization activity