Hs00508507_cn

• Gene Symbol: OAS1
• Assay Reference Genome Location: Chr.12:112908812 on build GRCh38
• Cytoband: 12q24.13

Target Gene Details

• Entrez Gene ID: 4938
• Gene Name: 2'-5'-oligoadenylate synthetase 1
• Gene Aliases: E18/E16, IFI-4, OIAS, OIASI
• Location: Chr.12:112906777-112932190 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OAS1	NM_001032409.2			NP_001027581.1
	NM_001320151.1			NP_001307080.1
	NM_002534.3			NP_002525.2
	NM_016816.3			NP_058132.2
	XM_006719434.1			XP_006719497.1
	XM_011538413.1			XP_011536715.1
	XM_017019361.1			XP_016874850.1
	XM_017019362.1			XP_016874851.1
	AJ629455.1			CAF33358.1
	AK223006.1			BAD96726.1
	AK225384.1
	AK291003.1
	AK300346.1
	AK301498.1
	AY730627.1			AAW63049.1
	AY730628.1			AAW63050.1
	BC000562.2
	BC061587.1			AAH61587.1
	BC071981.1
	BT006785.1			AAP35431.1
	D00068.1			BAA00047.1
	X02874.1			CAA26633.1
	X04371.1			CAB51602.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832515	Chr.12:112778024 - 112926931 on Build GRCh38	Gain	OAS1 RPH3A
nsv1042636	Chr.12:112627854 - 113014974 on Build GRCh38	Gain	OAS1 MIR1302-1 OAS2 RPH3A OAS3
nsv832516	Chr.12:112883300 - 113040797 on Build GRCh38	Gain	OAS1 OAS2 RPH3A OAS3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

nucleotidyltransferase

Gene Ontology Categories:

Process(es)

glucose metabolic process
response to virus
glucose homeostasis
negative regulation of viral genome replication
defense response to virus
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway

Function(s)

2'-5'-oligoadenylate synthetase activity
double-stranded RNA binding
protein binding
ATP binding
metal ion binding