Hs00529588_cn

• Gene Symbol: PTPN23
• Assay Reference Genome Location: Chr.3:47396165 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 25930
• Gene Name: protein tyrosine phosphatase, non-receptor type 23
• Gene Aliases: HD-PTP, HDPTP, PTP-TD14
• Location: Chr.3:47380982-47413441 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN23	NM_001304482.1			NP_001291411.1
	NM_015466.3			NP_056281.1
	XM_005265031.2			XP_005265088.2
	AB025194.1			BAB19280.1
	AB040904.2
	AF290614.1			AAK28025.1
	AK055157.1
	AK289502.1
	AK295877.1
	AK295888.1
	AK299906.1
	BC089042.1			AAH89042.1
	DA093189.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3802	Chr.3:47355184 - 47400461 on Build GRCh38	Deletion	PTPN23
nsv3803	Chr.3:47372642 - 47404507 on Build GRCh38	Insertion	PTPN23
nsv428417	Chr.3:46638962 - 47778557 on Build GRCh38	Loss	PTH1R PRSS43 PRSS45 ELP6 CSPG5 SETD2 MYL3 SNORD13P3 KLHL18 PRSS46 NRADDP SMARCC1 ALS2CL KIF9-AS1 NBEAL2 PRSS42 CCDC12 KIF9 SCAP PRSS50 PTPN23 TMIE

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

negative regulation of epithelial cell migration
protein transport
peptidyl-tyrosine dephosphorylation
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
cilium morphogenesis
positive regulation of homophilic cell adhesion
positive regulation of adherens junction organization
positive regulation of early endosome to late endosome transport

Function(s)

protein tyrosine phosphatase activity
protein binding
protein kinase binding