Hs00536745_cn

• Gene Symbol: NFS1
• Assay Reference Genome Location: Chr.20:35669574 on build GRCh38
• Cytoband: 20q11.22

Target Gene Details

• Entrez Gene ID: 9054
• Gene Name: NFS1 cysteine desulfurase
• Gene Aliases: HUSSY-08, IscS, NIFS
• Location: Chr.20:35668688-35699365 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NFS1	NM_001198989.1	12	1346	NP_001185918.1
	NM_021100.4	13	1499	NP_066923.3
	NR_037570.2	14	1621
	AF097025.2	13	1485	AAD09187.2
	AJ010952.1	9	1007	CAA09424.1
	AK001265.1	13	1484
	AK001470.1	13	1495
	AK056242.1	13	1770
	AK091049.1	5	2041
	AK223239.1	13	1485	BAD96959.1
	AK297969.1	14	1608
	AK301969.1	10	927
	AK302023.1	12	1333
	BC065560.1	13	1471	AAH65560.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526188	Chr.20:35576541 - 36019079 on Build GRCh38	Gain	CNBD2 FER1L4 SCAND1 PHF20 RBM12 NFS1 CPNE1 SPAG4 ROMO1 RBM39

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
protein complex assembly
Mo-molybdopterin cofactor biosynthetic process
iron incorporation into metallo-sulfur cluster
molybdopterin cofactor biosynthetic process
small molecule metabolic process
[2Fe-2S] cluster assembly

Function(s)

protein binding
pyridoxal phosphate binding
cysteine desulfurase activity
protein homodimerization activity
metal ion binding
iron-sulfur cluster binding