Hs00546591_cn

• Gene Symbol: CDCA3
• Assay Reference Genome Location: Chr.12:6846994 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 83461
• Gene Name: cell division cycle associated 3
• Gene Aliases: GRCC8, TOME-1
• Location: Chr.12:6844796-6852066 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDCA3	NM_001297603.1			NP_001284532.1
	AK092246.1
	AK093805.1
	AK097957.1

Target Gene Details

• Entrez Gene ID: 2784
• Gene Name: G protein subunit beta 3
• Gene Aliases: CSNB1H
• Location: Chr.12:6840854-6847400 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GNB3	NM_001297571.1	10	1326	NP_001284500.1
	NM_002075.3	10	1329	NP_002066.1
	XM_011520953.2	9	2250	XP_011519255.1
	AB209283.1	9	2470	BAD92520.1
	AB593098.1	10	1255
	AB593099.1	10	1254
	BC000115.1	10	1242	AAH00115.1
	BC002454.2	10	1249	AAH02454.1
	BC015920.1	10	1079	AAH15920.1
	M31328.1	9	1125	AAA52582.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv557261	Chr.12:6839304 - 6924660 on Build GRCh38	Loss	SPSB2 ENO2 LRRC23 CDCA3 P3H3 USP5 LOC105369632 ATN1 RPL13P5 DSTNP2 TPI1 GNB3
nsv832324	Chr.12:6780297 - 6932306 on Build GRCh38	Loss	ENO2 CD4 LRRC23 CDCA3 P3H3 USP5 DSTNP2 SPSB2 LOC105369632 GPR162 ATN1 RPL13P5 TPI1 GNB3
esv3580405	Chr.12:6826466 - 6903969 on Build GRCh38	Gain	SPSB2 CDCA3 P3H3 USP5 LOC105369632 GPR162 RPL13P5 DSTNP2 TPI1 GNB3
nsv832323	Chr.12:6662233 - 6856559 on Build GRCh38	Loss	CD4 CDCA3 P3H3 USP5 PIANP PTMS ZNF384 ING4 COPS7A MLF2 GPR162 LAG3 GNB3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

mitotic nuclear division
biological_process
protein ubiquitination
cell division
protein folding
G-protein coupled receptor signaling pathway
regulation of blood pressure
cellular response to glucagon stimulus

Function(s)

molecular_function
protein binding
GTPase activity
signal transducer activity
spectrin binding
GTPase binding