Hs00625705_cn

• Gene Symbol: TRPM2
• Assay Reference Genome Location: Chr.21:44423688 on build GRCh38
• Cytoband: 21q22.3

Target Gene Details

• Entrez Gene ID: 7226
• Gene Name: transient receptor potential cation channel subfamily M member 2
• Gene Aliases: EREG1, KNP3, LTRPC2, LTrpC-2, NUDT9H, NUDT9L1, TRPC7
• Location: Chr.21:44350112-44443081 on Build GRCh38
• Assay Gene Location: Overlaps Intron 25 - Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRPM2	NM_001320350.1			NP_001307279.1
	NM_001320351.1			NP_001307280.1
	NM_003307.3			NP_003298.1
	NR_038257.1
	XM_005261171.3			XP_005261228.1
	XM_011529736.2			XP_011528038.1
	XM_017028456.1			XP_016883945.1
	XM_017028457.1			XP_016883946.1
	AB001535.1			BAA34700.1
	AB166745.1			BAD83705.1
	AB166746.1			BAD83706.1
	AJ417076.1			CAD01139.1
	AJ878416.1			CAI47593.1
	AK301451.1
	BC112342.1
	R85260.1	3	303

Target Gene Details

• Entrez Gene ID: 101928607
• Gene Name: TRPM2 antisense RNA
• Gene Aliases: TRPM2-AS1
• Location: Chr.21:44414590-44425563 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRPM2-AS	NR_109964.1
	EU362988.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv519245	Chr.21:44413029 - 44429252 on Build GRCh38	Loss	TRPM2-AS TRPM2
nsv953646	Chr.21:44279118 - 44523117 on Build GRCh38	Deletion	TSPEAR-AS1 TSPEAR-AS2 TRPM2-AS LRRC3-AS1 LRRC3 AIRE LOC100505727 C21orf2 PFKL TSPEAR TRPM2
nsv1058359	Chr.21:44304172 - 44547662 on Build GRCh38	Gain	TSPEAR-AS1 TSPEAR-AS2 TRPM2-AS LRRC3-AS1 LRRC3 LOC100505727 C21orf2 PFKL TSPEAR TRPM2 KRTAP10-1
esv2723638	Chr.21:44249174 - 44593709 on Build GRCh38	Deletion	KRTAP10-2 TSPEAR-AS1 LRRC3-AS1 KRTAP10-5 LOC100505727 C21orf2 PFKL TSPEAR TRPM2 KRTAP10-4 KRTAP10-3 TSPEAR-AS2 TRPM2-AS LRRC3 AIRE DNMT3L KRTAP10-1 KRTAP10-6 LOC105372833
nsv509800	Chr.21:44284048 - 44471571 on Build GRCh38	Insertion	TRPM2-AS LRRC3-AS1 LRRC3 AIRE C21orf2 PFKL TRPM2
nsv587740	Chr.21:44209682 - 44429981 on Build GRCh38	Loss	TRPM2-AS AIRE DNMT3L ICOSLG C21orf2 PFKL TRPM2 LOC105372833
nsv587781	Chr.21:44344514 - 44447588 on Build GRCh38	Loss	TRPM2-AS TRPM2
esv33817	Chr.21:43749531 - 44647625 on Build GRCh38	Loss	KRTAP10-2 TSPEAR-AS1 LRRC3-AS1 KRTAP10-5 KRTAP10-11 AATBC LOC100505727 PFKL TRPM2 TRAPPC10 KRTAP10-4 TRPM2-AS LRRC3 PDXK AGPAT3 RRP1 C21orf33 KRTAP10-1 KRTAP10-6 LOC105372833 CSTB KRTAP10-8 ICOSLG C21orf2 PWP2 TSPEAR KRTAP10-9 KRTAP10-10 KRTAP10-3 KRTAP10-7 TSPEAR-AS2 AIRE DNMT3L

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ion channel, transporter

Gene Ontology Categories:

Process(es)

calcium ion transport
response to oxidative stress
positive regulation of insulin secretion
sodium ion transmembrane transport
estrous cycle
calcium ion transmembrane transport
calcium ion import across plasma membrane
positive regulation of oxidative stress-induced neuron death

Function(s)

calcium channel activity
sodium channel activity
ADP-ribose diphosphatase activity