Hs00637509_cn

• Gene Symbol: CEP72
• Assay Reference Genome Location: Chr.5:662578 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 55722
• Gene Name: centrosomal protein 72
• Gene Aliases: -
• Location: Chr.5:612290-663500 on Build GRCh38
• Assay Gene Location: Within Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CEP72	XM_011514063.1			XP_011512365.1

Target Gene Details

• Entrez Gene ID: 11076
• Gene Name: tubulin polymerization promoting protein
• Gene Aliases: TPPP/p25, TPPP1, p24, p25, p25alpha
• Location: Chr.5:659862-730454 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPPP	NM_007030.2	4	3306	NP_008961.1
	XM_005248237.3	4	3371	XP_005248294.2
	XM_017008993.1	4	5502	XP_016864482.1
	XM_017008994.1	6	3357	XP_016864483.1
	AB017016.1	4	3217	BAA36164.1
	AK098392.1
	BC040496.1	4	3230	AAH40496.1
	BC131506.1	3	3202

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5521n100	Chr.5:568570 - 685633 on Build GRCh38	Gain	TPPP LOC101929895 CEP72 LOC100996325
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	HRAT5 MIR4456 AHRR ZDHHC11B LOC101929895 PLEKHG4B EXOC3-AS1 PDCD6 LOC100996325 LOC100288152 SDHA TPPP LRRC14B EXOC3 SLC9A3 CEP72 CCDC127 ZDHHC11 PP7080
nsv4675	Chr.5:658779 - 844631 on Build GRCh38	Deletion	TPPP ZDHHC11B LOC101929895 CEP72 ZDHHC11
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	MIR4456 AHRR ZDHHC11B LOC101929895 EXOC3-AS1 LOC100996325 LOC100288152 TPPP EXOC3 SLC9A3 CEP72 ZDHHC11 PP7080
esv2759316	Chr.5:620048 - 1161361 on Build GRCh38	Gain+Loss	TPPP LOC100506688 ZDHHC11B BRD9 TRIP13 LOC101929895 CEP72 NKD2 ZDHHC11 SLC12A7 MIR4635
dgv7n29	Chr.5:609831 - 820394 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72 LOC100996325 ZDHHC11
nsv1033593	Chr.5:609765 - 685633 on Build GRCh38	Gain	TPPP LOC101929895 CEP72 LOC100996325
nsv596703	Chr.5:539195 - 685633 on Build GRCh38	Gain	TPPP LOC101929895 CEP72 LOC100996325
nsv596629	Chr.5:457146 - 1468172 on Build GRCh38	Gain	LINC01511 ZDHHC11B BRD9 TRIP13 NKD2 SLC6A3 TERT LPCAT1 TPPP LOC100506688 EXOC3 CEP72 CLPTM1L ZDHHC11 SLC12A7 MIR4635 MIR4457 CTD-3080P12.3 MIR4456 LOC101929895 LOC100996325 LOC100288152 SLC6A18 SLC9A3 SLC6A19 PP7080
nsv471627	Chr.5:609832 - 826405 on Build GRCh38	Gain+Loss	TPPP ZDHHC11B LOC101929895 CEP72 LOC100996325 ZDHHC11
nsv509042	Chr.5:483833 - 720373 on Build GRCh38	Insertion	TPPP MIR4456 ZDHHC11B LOC101929895 SLC9A3 CEP72 LOC100996325
nsv950622	Chr.5:661486 - 693585 on Build GRCh38	Deletion	TPPP LOC101929895 CEP72
nsv1161198	Chr.5:654181 - 817735 on Build GRCh38	Duplication	TPPP ZDHHC11B LOC101929895 CEP72 ZDHHC11
esv3575804	Chr.5:588315 - 676732 on Build GRCh38	Gain	TPPP LOC101929895 CEP72 LOC100996325
dgv922n67	Chr.5:662068 - 788975 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72
dgv195e55	Chr.5:659490 - 823705 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72 ZDHHC11
dgv5522n100	Chr.5:625176 - 809679 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72 ZDHHC11
nsv596710	Chr.5:595755 - 729907 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72 LOC100996325
dgv131e203	Chr.5:653466 - 874903 on Build GRCh38	Gain+Loss	TPPP ZDHHC11B BRD9 LOC101929895 CEP72 ZDHHC11
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	TPPP MIR4456 AHRR EXOC3 LOC101929895 SLC9A3 CEP72 EXOC3-AS1 LOC100996325 LOC100288152 PP7080
dgv5524n100	Chr.5:659283 - 825526 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72 ZDHHC11
dgv5523n100	Chr.5:653454 - 790474 on Build GRCh38	Gain	TPPP ZDHHC11B LOC101929895 CEP72
nsv461894	Chr.5:593968 - 685633 on Build GRCh38	Gain	TPPP LOC101929895 CEP72 LOC100996325

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
spindle organization
centriole replication
gamma-tubulin complex localization
regulation of protein localization to centrosome
microtubule bundle formation
positive regulation of protein complex assembly
positive regulation of protein polymerization
microtubule polymerization

Function(s)

protein binding
identical protein binding
microtubule binding
tubulin binding