Hs00643953_cn

• Gene Symbol: MMP15
• Assay Reference Genome Location: Chr.16:58040695 on build GRCh38
• Cytoband: 16q21

Target Gene Details

• Entrez Gene ID: 4324
• Gene Name: matrix metallopeptidase 15
• Gene Aliases: MMP-15, MT2-MMP, MT2MMP, MTMMP2, SMCP-2
• Location: Chr.16:58025566-58046901 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MMP15	NM_002428.3			NP_002419.1
	BC036495.1			AAH36495.1
	BC055428.1			AAH55428.1
	BT006715.1			AAP35361.1
	D85510.1			BAA22225.1
	D86331.1			BAA13071.1
	Z48482.1			CAA88373.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv572760	Chr.16:58029609 - 58119987 on Build GRCh38	Loss	MMP15 CFAP20
nsv572761	Chr.16:58035317 - 58046468 on Build GRCh38	Loss	MMP15
esv3638716	Chr.16:58011317 - 58046443 on Build GRCh38	Loss	USB1 MMP15
nsv572762	Chr.16:58035565 - 58051978 on Build GRCh38	Loss	MMP15
dgv525e214	Chr.16:58007762 - 58046443 on Build GRCh38	Gain	USB1 MMP15

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

cellular protein modification process
proteolysis
extracellular matrix disassembly
collagen catabolic process
response to estradiol
endodermal cell differentiation
positive regulation of catalytic activity

Function(s)

metalloendopeptidase activity
serine-type endopeptidase activity
calcium ion binding
protein binding
enzyme activator activity
zinc ion binding