Hs00647111_cn

• Gene Symbol: ADAM12
• Assay Reference Genome Location: Chr.10:126016034 on build GRCh38
• Cytoband: 10q26.2

Target Gene Details

• Entrez Gene ID: 8038
• Gene Name: ADAM metallopeptidase domain 12
• Gene Aliases: ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA
• Location: Chr.10:126012385-126388558 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAM12	NM_001288973.1	23	4379	NP_001275902.1
	NM_003474.5	23	4388	NP_003465.3
	XM_017016705.1	22	4291	XP_016872194.1
	XM_017016706.1	13	3430	XP_016872195.1
	AF023476.2	23	4281	AAC08702.2
	KF444157.1	23	4379

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759788	Chr.10:125765331 - 126098133 on Build GRCh38	Gain	FANK1 BCCIP UROS MIR4484 MMP21 ADAM12 FANK1-AS1 DHX32

More Information

Additional Information:

For this assay, SNP(s) [rs116413422] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
cell adhesion
myoblast fusion

Function(s)

metalloendopeptidase activity
metallopeptidase activity
zinc ion binding
SH3 domain binding