Hs00648742_cn

• Gene Symbol: FOS
• Assay Reference Genome Location: Chr.14:75280905 on build GRCh38
• Cytoband: 14q24.3

Target Gene Details

• Entrez Gene ID: 2353
• Gene Name: Fos proto-oncogene, AP-1 transcription factor subunit
• Gene Aliases: AP-1, C-FOS, p55
• Location: Chr.14:75278778-75282234 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FOS	NM_005252.3	4	829	NP_005243.1
	AK097379.1	4	594
	AK290907.1	3	717
	AK291326.1	4	779
	AK298659.1	3	671
	BC004490.2	4	750	AAH04490.1
	BX647104.1	4	779
	CR541785.1	4	624	CAG46584.1
	CR542267.1	4	624	CAG47063.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832833	Chr.14:75100965 - 75304860 on Build GRCh38	Gain	FOS LINC01220 TMED10 NEK9

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

conditioned taste aversion
DNA methylation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
inflammatory response
transforming growth factor beta receptor signaling pathway
nervous system development
female pregnancy
aging
response to cold
response to light stimulus
response to gravity
response to toxic substance
sleep
cellular response to extracellular stimulus
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
response to cytokine
cellular response to reactive oxygen species
response to immobilization stress
skeletal muscle cell differentiation
response to muscle stretch
Fc-epsilon receptor signaling pathway
response to drug
positive regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of sequence-specific DNA binding transcription factor activity
response to corticosterone
response to cAMP
SMAD protein signal transduction
cellular response to calcium ion
positive regulation of pri-miRNA transcription from RNA polymerase II promoter

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
R-SMAD binding