Hs00654329_cn

• Gene Symbol: PIAS2
• Assay Reference Genome Location: Chr.18:46836484 on build GRCh38
• Cytoband: 18q21.1

Target Gene Details

• Entrez Gene ID: 9063
• Gene Name: protein inhibitor of activated STAT 2
• Gene Aliases: ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4
• Location: Chr.18:46803224-46920167 on Build GRCh38
• Assay Gene Location: Overlaps Intron 16 - Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIAS2	NM_001324046.1			NP_001310975.1
	NM_001324047.1			NP_001310976.1
	NM_001324048.1			NP_001310977.1
	NM_001324049.1			NP_001310978.1
	NM_001324051.1			NP_001310980.1
	NM_001324052.1			NP_001310981.1
	NM_001324053.1			NP_001310982.1
	NM_001324054.1			NP_001310983.1
	NM_001324055.1			NP_001310984.1
	NM_001324057.1			NP_001310986.1
	NM_001324058.1			NP_001310987.1
	NM_001324059.1			NP_001310988.1
	NM_001324060.1			NP_001310989.1
	NM_004671.4			NP_004662.2
	NM_173206.3			NP_775298.1
	NR_136684.1
	NR_136685.1
	XM_005258377.3			XP_005258434.1
	XM_005258379.3			XP_005258436.1
	XM_006722571.3			XP_006722634.1
	XM_006722572.3			XP_006722635.1
	XM_006722573.2			XP_006722636.1
	XM_011526258.2			XP_011524560.1
	XM_011526259.2			XP_011524561.1
	XM_017026068.1			XP_016881557.1
	XM_017026069.1			XP_016881558.1
	XM_017026070.1			XP_016881559.1
	XM_017026071.1			XP_016881560.1
	XM_017026072.1			XP_016881561.1
	AF077953.1			AAC36704.1
	AF077954.1			AAC36705.1
	AF361054.1			AAK48938.1
	AK294801.1
	AK308143.1
	BC015190.1			AAH15190.1
	BC111060.1			AAI11061.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9629	Chr.18:46684730 - 47231140 on Build GRCh38	Gain+Loss	TCEB3C PIAS2 HDHD2 IER3IP1 LOC107983955 TCEB3CL SKOR2 TCEB3CL2 KATNAL2 TCEB3B ST8SIA5
esv2763189	Chr.18:46835816 - 46935421 on Build GRCh38	Gain	PIAS2 KATNAL2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
protein sumoylation
androgen receptor signaling pathway
regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of androgen receptor signaling pathway

Function(s)

DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity