Hs00671287_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67154932 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1
	AK315654.1
	BC004491.2			AAH04491.1
	BT006934.1			AAP35580.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	LRRC29 HSF4 HSD11B2 EDC4 TPPP3 LRRC36 NOL3 C16orf86 TSNAXIP1 RANBP10 NUTF2 LOC105369155 LOC107984813 MIR328 E2F4 KCTD19 DPEP2 FHOD1 GFOD2 AGRP CARMIL2 ATP6V0D1 LCAT THAP11 KIAA0895L DPEP3 NRN1L SLC9A5 TRADD LOC100131303 SLC12A4 CENPT FBXL8 PLEKHG4 EXOC3L1 CTRL LOC100505942 ENKD1 ACD ZDHHC1 DDX28 DUS2 ELMO3 FAM65A PARD6A TMEM208 CTCF PSMB10 PSKH1
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	LRRC29 LOC105369155 MIR328 C16orf70 HSF4 E2F4 FHOD1 SLC9A5 TRADD B3GNT9 FBXL8 PLEKHG4 ELMO3 EXOC3L1 TMEM208 KIAA0895L NOL3
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	LRRC29 LOC105369155 MIR328 C16orf70 HSF4 E2F4 FHOD1 TRADD B3GNT9 FBXL8 ELMO3 EXOC3L1 TMEM208 KIAA0895L NOL3
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	LRRC29 C16orf70 HSF4 HSD11B2 EDC4 B3GNT9 TPPP3 LRRC36 NOL3 C16orf86 TSNAXIP1 RANBP10 NUTF2 LOC105369155 LOC107984813 MIR328 E2F4 KCTD19 DPEP2 FHOD1 GFOD2 AGRP CARMIL2 ATP6V0D1 LCAT THAP11 KIAA0895L DPEP3 NRN1L SLC9A5 TRADD LOC100131303 SLC12A4 CENPT FBXL8 PLEKHG4 EXOC3L1 CTRL LOC100505942 ENKD1 ACD ZDHHC1 DDX28 DUS2 ELMO3 FAM65A PARD6A TMEM208 CTCF PSMB10 PSKH1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding