Hs00683696_cn

• Gene Symbol: TNKS
• Assay Reference Genome Location: Chr.8:9580243 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 8658
• Gene Name: tankyrase
• Gene Aliases: ARTD5, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5
• Location: Chr.8:9555229-9782346 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNKS	NM_003747.2	2	763	NP_003738.2
	XM_006716263.3	2	1469	XP_006716326.1
	XM_011543845.2	2	1469	XP_011542147.1
	XM_011543846.2	2	1469	XP_011542148.1
	XM_011543847.2	2	1468	XP_011542149.1
	AF082556.1	2	763	AAC79841.1
	AF082557.1	1	59	AAC79842.1
	AK301798.1	2	684
	AK302031.1	2	784
	AK302534.1	2	437
	BC098394.1	2	786	AAH98394.1

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

protein polyubiquitination
protein ADP-ribosylation
mitotic spindle organization
mitotic nuclear division
protein transport
Wnt signaling pathway
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
regulation of telomere maintenance via telomerase
positive regulation of telomere maintenance via telomerase
positive regulation of transcription from RNA polymerase II promoter
mRNA transport
spindle assembly
cell division
positive regulation of telomerase activity
protein localization to chromosome, telomeric region
protein poly-ADP-ribosylation
protein auto-ADP-ribosylation
positive regulation of canonical Wnt signaling pathway
positive regulation of telomere capping
negative regulation of telomere maintenance via telomere lengthening
negative regulation of telomeric DNA binding
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

Function(s)

NAD+ ADP-ribosyltransferase activity
protein binding
zinc ion binding
histone binding