Hs00744580_cn

• Gene Symbol: SIPA1
• Assay Reference Genome Location: Chr.11:65649680 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 6494
• Gene Name: signal-induced proliferation-associated 1
• Gene Aliases: SPA1
• Location: Chr.11:65638107-65650930 on Build GRCh38
• Assay Gene Location: Overlaps Exon 14 - Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIPA1	NM_006747.3			NP_006738.3
	NM_153253.29			NP_694985.29
	XM_005274189.2			XP_005274246.1
	XM_011545214.1			XP_011543516.1
	AB005666.1			BAA22197.1
	AF029789.1			AAC32547.1
	AK303551.1
	AK308234.1
	BC010492.1			AAH10492.1
	BC110353.1			AAI10354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1969n54	Chr.11:65568234 - 65663889 on Build GRCh38	Loss	PCNX3 KCNK7 SIPA1 RELA EHBP1L1 MAP3K11 MIR4489 FAM89B MIR4690 SSSCA1 SSSCA1-AS1
nsv951018	Chr.11:65525430 - 65662029 on Build GRCh38	Deletion	PCNX3 KCNK7 EHBP1L1 MAP3K11 MIR4690 SIPA1 RELA MIR4489 FAM89B LTBP3 SSSCA1 SCYL1 SSSCA1-AS1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

cytoskeleton organization
negative regulation of cell adhesion
signal transduction
cell proliferation
negative regulation of cell growth
intracellular signal transduction
cellular response to water deprivation
positive regulation of GTPase activity
negative regulation of cell cycle
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
protein C-terminus binding