Hs00754851_cn

• Gene Symbol: TNNI2
• Assay Reference Genome Location: Chr.11:1840873 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 7136
• Gene Name: troponin I2, fast skeletal type
• Gene Aliases: AMCD2B, DA2B, FSSV, fsTnI
• Location: Chr.11:1839003-1841680 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNNI2	NM_001145829.1			NP_001139301.1
	NM_001145841.1			NP_001139313.1
	NM_003282.3			NP_003273.1
	AW984315.1
	BC032148.2			AAH32148.1
	BI833431.1
	BP233165.1
	BQ926240.1
	L21715.1			AAA19813.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522320	Chr.11:1835882 - 1996938 on Build GRCh38	Loss	SNORD131 LSP1 MRPL23-AS1 H19 TNNT3 MRPL23 LINC01219 SYT8 MIR4298 MIR675 LINC01150 HOTS TNNI2 MIR7847
nsv1047474	Chr.11:1803515 - 2043381 on Build GRCh38	Gain	SNORD131 LSP1 MRPL23-AS1 H19 TNNT3 MRPL23 LINC01219 SYT8 MIR4298 MIR675 LINC01150 HOTS TNNI2 MIR7847
nsv553052	Chr.11:1835294 - 1841679 on Build GRCh38	Gain	TNNI2 SYT8
nsv553055	Chr.11:1838288 - 1841209 on Build GRCh38	Loss	TNNI2
nsv553050	Chr.11:1813024 - 1884944 on Build GRCh38	Loss	MIR4298 LSP1 TNNI2 MIR7847 SYT8
nsv553053	Chr.11:1836040 - 1887776 on Build GRCh38	Loss	MIR4298 LSP1 TNNI2 MIR7847 SYT8
nsv951281	Chr.11:1821171 - 1858170 on Build GRCh38	Deletion	LSP1 TNNI2 SYT8
nsv553054	Chr.11:1837032 - 1853837 on Build GRCh38	Loss	LSP1 TNNI2 SYT8
esv29980	Chr.11:1820597 - 2097889 on Build GRCh38	Loss	SNORD131 LSP1 MRPL23-AS1 H19 TNNT3 MRPL23 LINC01219 SYT8 MIR4298 MIR675 LINC01150 HOTS TNNI2 MIR7847
nsv553047	Chr.11:1733170 - 2418537 on Build GRCh38	Gain	SNORD131 C11orf21 CD81 IFITM10 MRPL23-AS1 H19 INS TSSC4 TNNT3 IGF2-AS LINC01219 IGF2 INS-IGF2 CTSD ASCL2 TRPM5 MIR7847 LSP1 MRPL23 MIR483 SYT8 CD81-AS1 MIR4298 MIR675 TSPAN32 MIR4686 TH LINC01150 HOTS TNNI2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

skeletal muscle contraction
regulation of muscle contraction
muscle filament sliding
positive regulation of transcription, DNA-templated
cardiac muscle contraction

Function(s)

actin binding
protein binding
troponin T binding