Hs00758128_cn

• Gene Symbol: IQSEC1
• Assay Reference Genome Location: Chr.3:12913447 on build GRCh38
• Cytoband: 3p25.2

Target Gene Details

• Entrez Gene ID: 9922
• Gene Name: IQ motif and Sec7 domain 1
• Gene Aliases: ARF-GEP100, ARFGEP100, BRAG2, GEP100
• Location: Chr.3:12897043-13282998 on Build GRCh38
• Assay Gene Location: Overlaps Intron 19 - Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IQSEC1	NM_001134382.2			NP_001127854.1
	NM_014869.6			NP_055684.3
	XM_011534304.2			XP_011532606.1
	XM_011534305.2			XP_011532607.1
	XM_011534306.2			XP_011532608.1
	XM_011534307.2			XP_011532609.1
	XM_011534308.2			XP_011532610.1
	XM_011534310.2			XP_011532612.1
	XM_011534311.2			XP_011532613.1
	XM_011534312.2			XP_011532614.1
	XM_011534313.2			XP_011532615.1
	XM_011534314.2			XP_011532616.1
	XM_011534315.2			XP_011532617.1
	XM_017007581.1			XP_016863070.1
	XM_017007582.1			XP_016863071.1
	AB018306.1			BAA34483.2
	AK294525.1
	AY653734.1			AAT72063.1
	BC010267.1			AAH10267.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv589716	Chr.3:12820109 - 12926604 on Build GRCh38	Loss	IQSEC1 LOC105376955 RPL32 SNORA7A CAND2
nsv589715	Chr.3:12813127 - 12976988 on Build GRCh38	Loss	IQSEC1 LOC105376955 RPL32 SNORA7A CAND2
nsv589718	Chr.3:12898047 - 12960142 on Build GRCh38	Loss	IQSEC1
esv3893663	Chr.3:12822887 - 12921716 on Build GRCh38	Gain	IQSEC1 LOC105376955 RPL32 SNORA7A CAND2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

actin cytoskeleton organization
regulation of ARF protein signal transduction
positive regulation of GTPase activity

Function(s)

ARF guanyl-nucleotide exchange factor activity
lipid binding