Hs00760681_cn

• Gene Symbol: DGKZ
• Assay Reference Genome Location: Chr.11:46376417 on build GRCh38
• Cytoband: 11p11.2

Target Gene Details

• Entrez Gene ID: 8525
• Gene Name: diacylglycerol kinase zeta
• Gene Aliases: DAGK5, DAGK6, DGK-ZETA, hDGKzeta
• Location: Chr.11:46332905-46380554 on Build GRCh38
• Assay Gene Location: Overlaps Exon 28 - Intron 28

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DGKZ	NM_001105540.1			NP_001099010.1
	NM_001199266.1			NP_001186195.1
	NM_001199267.1			NP_001186196.1
	NM_001199268.1			NP_001186197.1
	NM_003646.3			NP_003637.2
	NM_201532.2			NP_963290.1
	NM_201533.3			NP_963291.2
	XM_005253181.3			XP_005253238.1
	XM_005253182.3			XP_005253239.1
	XM_006718354.1			XP_006718417.1
	XM_006718355.2			XP_006718418.1
	XM_011520422.1			XP_011518724.1
	XM_011520423.1			XP_011518725.1
	XM_017018455.1			XP_016873944.1
	XM_017018456.1			XP_016873945.1
	XM_017018457.1			XP_016873946.1
	AB209635.1			BAD92872.1
	AK124594.1			BAC85894.1
	AK126970.1			BAC86770.1
	AK225774.1
	AK293615.1
	AK294888.1
	AK300577.1
	AK303322.1
	AK312398.1
	BC008018.1			AAH08018.1
	BC041770.1			AAH41770.1
	BX648433.1
	U51477.1			AAC50478.1
	U94905.1			AAB60859.1

Target Gene Details

• Entrez Gene ID: 100616368
• Gene Name: microRNA 4688
• Gene Aliases: mir-4688
• Location: Chr.11:46376402-46376484 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR4688	NR_039837.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3626185	Chr.11:46361673 - 46411056 on Build GRCh38	Loss	DGKZ MDK AMBRA1 MIR4688 CHRM4
esv3626183	Chr.11:46227941 - 46507334 on Build GRCh38	Gain	CREB3L1 MIR3160-1 RPS10P19 DGKZ MDK AMBRA1 MIR4688 CHRM4 MIR3160-2
nsv951610	Chr.11:46367051 - 46392750 on Build GRCh38	Deletion	DGKZ MDK MIR4688 CHRM4
nsv554202	Chr.11:46312688 - 46448350 on Build GRCh38	Loss	CREB3L1 RPS10P19 DGKZ MDK AMBRA1 MIR4688 CHRM4
nsv825867	Chr.11:46281633 - 46404063 on Build GRCh38	Gain	CREB3L1 DGKZ MDK AMBRA1 MIR4688 CHRM4
nsv554201	Chr.11:46260284 - 46401136 on Build GRCh38	Loss	CREB3L1 DGKZ MDK AMBRA1 MIR4688 CHRM4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
cell migration
platelet activation
intracellular signal transduction

Function(s)

diacylglycerol kinase activity
protein binding
ATP binding
metal ion binding