Hs00775170_cn

• Gene Symbol: UBE2K
• Assay Reference Genome Location: Chr.4:39698373 on build GRCh38
• Cytoband: 4p14

Target Gene Details

• Entrez Gene ID: 3093
• Gene Name: ubiquitin conjugating enzyme E2 K
• Gene Aliases: E2-25K, HIP2, HYPG, LIG, UBC1
• Location: Chr.4:39698044-39782792 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2K	NM_001111112.1			NP_001104582.1
	NM_001111113.1			NP_001104583.1
	NM_001312646.1			NP_001299575.1
	NM_001312647.1			NP_001299576.1
	NM_001312648.1			NP_001299577.1
	NM_005339.4			NP_005330.1
	AB022435.1			BAA78555.1
	AB022436.1			BAA78556.1
	AK093533.1
	AK291454.1
	AK295846.1
	AK307130.1
	AK315524.1
	BC022804.1			AAH22804.1
	BC050600.1			AAH50600.1
	CX786829.1
	DA526283.1
	U58522.1			AAC50633.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv516320	Chr.4:39697118 - 39709027 on Build GRCh38	Loss	UBE2K
nsv436937	Chr.4:39692694 - 39736585 on Build GRCh38	Loss	UBE2K

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
positive regulation of peptidyl-threonine phosphorylation
free ubiquitin chain polymerization
regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular response to interferon-beta
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of type I interferon-mediated signaling pathway
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein K48-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
ubiquitin-ubiquitin ligase activity