Hs00780466_cn

• Gene Symbol: IARS
• Assay Reference Genome Location: Chr.9:92247522 on build GRCh38
• Cytoband: 9q22.31

Target Gene Details

• Entrez Gene ID: 3376
• Gene Name: isoleucyl-tRNA synthetase
• Gene Aliases: IARS1, ILERS, ILRS, IRS, PRO0785
• Location: Chr.9:92210207-92293756 on Build GRCh38
• Assay Gene Location: Overlaps Intron 25 - Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IARS	NM_002161.5			NP_002152.2
	NM_013417.3			NP_038203.2
	NR_073446.1
	AB209234.1			BAD92471.1
	AK293014.1
	AK301272.1
	AK308202.1
	BC008318.1			AAH08318.2
	BC065552.1			AAH65552.1
	BX537417.1			CAD97659.1
	BX537429.1			CAD97671.1
	BX538109.1			CAD98022.1
	BX647071.1
	BX647236.1
	BX647430.1
	BX648567.1
	D28473.1			BAA05835.1
	U04953.1			AAA80153.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3891693	Chr.9:92163398 - 92538277 on Build GRCh38	Gain	NOL8 IARS MIR4670 ECM2 MIR3651 OMD ASPN SNORA84 CENPP OGN
nsv1046733	Chr.9:91928340 - 92376282 on Build GRCh38	Gain	NOL8 LINC00475 IARS LOC100128076 MIR3651 ROR2 SNORA84 CENPP SPTLC1
nsv6615	Chr.9:92224809 - 92258551 on Build GRCh38	Insertion	IARS

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

osteoblast differentiation
tRNA aminoacylation for protein translation
isoleucyl-tRNA aminoacylation
regulation of translational fidelity

Function(s)

tRNA binding
aminoacyl-tRNA editing activity
isoleucine-tRNA ligase activity
protein binding
ATP binding
GTPase binding