Hs00842823_cn

• Gene Symbol: KLK3
• Assay Reference Genome Location: Chr.19:50859572 on build GRCh38
• Cytoband: 19q13.33

Target Gene Details

• Entrez Gene ID: 354
• Gene Name: kallikrein related peptidase 3
• Gene Aliases: APS, KLK2A1, PSA, hK3
• Location: Chr.19:50854915-50860764 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLK3	NM_001030047.1			NP_001025218.1
	NM_001030048.1			NP_001025219.1
	NM_001648.2			NP_001639.1
	AF335477.1			AAL73204.1
	AF335478.1			AAL73205.1
	AJ310938.1			CAC41632.1
	AJ459782.1			CAD30844.1
	AJ459783.1			CAD30845.1
	AK312933.1
	AX772834.1	4	536	CAE06266.1
	BC005307.1			AAH05307.1
	BC050595.2			AAH50595.2
	BC056665.1			AAH56665.1
	BQ932072.1
	BT019862.1			AAV38665.1
	DQ641251.1
	M21895.1			AAA59995.1
	M21896.1			AAA59996.1
	M26663.1			AAA58802.1
	U17040.1			AAA56764.1
	X05332.1			CAA28947.1
	X07730.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2531	Chr.19:50830372 - 50875341 on Build GRCh38	Deletion	KLK3 KLK2 KLK15 LOC105372441
esv2763208	Chr.19:50858501 - 50873907 on Build GRCh38	Gain	KLK3 KLK2
nsv524465	Chr.19:50856831 - 50860142 on Build GRCh38	Loss	KLK3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease, serine protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

antibacterial peptide production
proteolysis
negative regulation of angiogenesis
cellular protein metabolic process

Function(s)

endopeptidase activity
serine-type endopeptidase activity
protein binding
serine-type peptidase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides