Hs00843631_cn

• Gene Symbol: ADORA1
• Assay Reference Genome Location: Chr.1:203128445 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 134
• Gene Name: adenosine A1 receptor
• Gene Aliases: RDC7
• Location: Chr.1:203127705-203167405 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA1	NM_000674.2			NP_000665.1
	NM_001048230.1			NP_001041695.1
	XM_005244901.1			XP_005244958.1
	XM_017000342.1			XP_016855831.1
	AK095060.1
	AK127752.1
	AK289928.1
	AK293647.1
	AK295584.1
	AK308733.1
	AK316106.1
	BC026340.1			AAH26340.1
	DA343445.1
	DB171678.1
	KC884744.1
	L22214.1			AAA17544.1
	S45235.1			AAB23388.1
	X68485.1			CAA48503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832370	Chr.1:202997191 - 203196105 on Build GRCh38	Loss	LOC100506747 CHI3L1 MYBPH MYOG PPFIA4 TMEM183A ADORA1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
temperature homeostasis
response to hypoxia
adenosine receptor signaling pathway
regulation of respiratory gaseous exchange by neurological system process
negative regulation of acute inflammatory response
negative regulation of leukocyte migration
positive regulation of peptide secretion
regulation of glomerular filtration
protein targeting to membrane
phagocytosis
inflammatory response
signal transduction
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cell-cell signaling
nervous system development
negative regulation of cell proliferation
negative regulation of glutamate secretion
lipid catabolic process
negative regulation of synaptic transmission, GABAergic
positive regulation of nucleoside transport
negative regulation of neurotrophin production
positive regulation of protein dephosphorylation
negative regulation of renal sodium excretion
negative regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of apoptotic process
positive regulation of potassium ion transport
positive regulation of epidermal growth factor-activated receptor activity
negative regulation of blood pressure
positive regulation of blood pressure
negative regulation of vasodilation
negative regulation of hormone secretion
cognition
detection of temperature stimulus involved in sensory perception of pain
negative regulation of lipid catabolic process
regulation of sensory perception of pain
negative regulation of synaptic transmission, glutamatergic
negative regulation of cardiac muscle contraction
excitatory postsynaptic potential
relaxation of vascular smooth muscle
negative regulation of mucus secretion
apoptotic signaling pathway
negative regulation of long term synaptic depression

Function(s)

G-protein coupled adenosine receptor activity
G-protein coupled receptor binding
purine nucleoside binding
phospholipase C activity
protein binding
heat shock protein binding
G-protein beta/gamma-subunit complex binding
heterotrimeric G-protein binding
protein heterodimerization activity