Hs00846751_cn

• Gene Symbol: DERL1
• Assay Reference Genome Location: Chr.8:123015145 on build GRCh38
• Cytoband: 8q24.13

Target Gene Details

• Entrez Gene ID: 79139
• Gene Name: derlin 1
• Gene Aliases: DER-1, DER1
• Location: Chr.8:123013164-123042423 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DERL1	NM_001134671.2	8	1299	NP_001128143.1
	NM_024295.5	8	1359	NP_077271.1
	XM_006716657.1	7	843	XP_006716720.1
	XM_011517299.1	7	1159	XP_011515601.1
	AK023846.1	6	4529
	AK124086.1	7	860
	AK303826.1
	AY358818.1	8	1237	AAQ89177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1032827	Chr.8:122655842 - 123258160 on Build GRCh38	Gain	LINC01151 TBC1D31 FAM83A ZHX2 C8orf76 MIR4663 ZHX1-C8orf76 FAM83A-AS1 DERL1 ZHX1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

response to unfolded protein
intracellular transport of viral protein in host cell
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol
positive regulation of protein ubiquitination
protein destabilization
positive regulation of protein binding
ERAD pathway
establishment of protein localization
protein homooligomerization
ER-associated misfolded protein catabolic process

Function(s)

protease binding
receptor activity
protein binding
ubiquitin protein ligase binding
MHC class I protein binding
ATPase binding
ubiquitin-specific protease binding