Hs00870425_cn

• Gene Symbol: PROK2
• Assay Reference Genome Location: Chr.3:71772304 on build GRCh38
• Cytoband: 3p13

Target Gene Details

• Entrez Gene ID: 60675
• Gene Name: prokineticin 2
• Gene Aliases: BV8, HH4, KAL4, MIT1, PK2
• Location: Chr.3:71771655-71785206 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PROK2	NM_001126128.1	4	964	NP_001119600.1
	NM_021935.3	3	901	NP_068754.1
	XM_017006974.1	4	898	XP_016862463.1
	AF182069.2	4	795	AAG16893.2
	AF333025.1	3	756	AAK49919.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv590600	Chr.3:71717301 - 71780868 on Build GRCh38	Loss	GPR27 PROK2 EIF4E3
nsv524847	Chr.3:71745256 - 71772339 on Build GRCh38	Loss	GPR27 PROK2 EIF4E3

More Information

Additional Information:

For this assay, SNP(s) [rs76187327] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

activation of MAPK activity
angiogenesis
chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
spermatogenesis
circadian rhythm
cell proliferation
positive regulation of cell proliferation
sensory perception of pain
negative regulation of apoptotic process
regulation of angiogenesis
positive regulation of smooth muscle contraction

Function(s)

G-protein coupled receptor binding