Hs00874552_cn

• Gene Symbol: SIRPB1
• Assay Reference Genome Location: Chr.20:1565026 on build GRCh38
• Cytoband: 20p13

Target Gene Details

• Entrez Gene ID: 10326
• Gene Name: signal regulatory protein beta 1
• Gene Aliases: CD172b, SIRP-BETA-1
• Location: Chr.20:1564193-1620457 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIRPB1	XM_005260641.3	6	1732	XP_005260698.1
	XM_005260643.3	5	1399	XP_005260700.1
	XM_005260644.3	4	1082	XP_005260701.1
	XM_017027577.1	6	2195	XP_016883066.1
	XM_017027581.1	7	2040	XP_016883070.1
	XM_017027582.1	7	2080	XP_016883071.1
	XM_017027585.1	5	1832	XP_016883074.1
	BC025286.1	4	1072	AAH25286.1
	BC075835.1	4	1072	AAH75835.1
	BC131747.1	4	1056
	BP268958.1
	Y10376.1	6	1711	CAA71404.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2424715	Chr.20:1564995 - 1565893 on Build GRCh38	Insertion	SIRPB1
nsv9775	Chr.20:1554339 - 1583014 on Build GRCh38	Loss	SIRPB1 SIRPD
nsv522008	Chr.20:1359746 - 1657932 on Build GRCh38	Gain	NSFL1C FKBP1A SIRPB1 SIRPG-AS1 SIRPB2 SIRPG SDCBP2-AS1 MIR6869 FKBP1A-SDCBP2 SIRPD
nsv1160672	Chr.20:1564764 - 1580934 on Build GRCh38	Deletion	SIRPB1
nsv510779	Chr.20:1528684 - 1633316 on Build GRCh38	Deletion	SIRPB1 SIRPG SIRPD
esv2758777	Chr.20:1496135 - 1698610 on Build GRCh38	Gain+Loss	SIRPB1 SIRPG-AS1 SIRPG SIRPD
nsv585206	Chr.20:1405829 - 1733716 on Build GRCh38	Gain	NSFL1C SIRPB1 SIRPG-AS1 SIRPB2 SIRPG SIRPD
esv33848	Chr.20:1565055 - 1570417 on Build GRCh38	Loss	SIRPB1
nsv833894	Chr.20:1538787 - 1772720 on Build GRCh38	Gain	SIRPB1 SIRPG-AS1 SIRPG SIRPD
esv3644980	Chr.20:1509522 - 1569123 on Build GRCh38	Gain	SIRPB1 SIRPD

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

signal transduction
cell surface receptor signaling pathway
innate immune response

Function(s)

protein binding