Hs00879452_cn

• Gene Symbol: OAS1
• Assay Reference Genome Location: Chr.12:112919487 on build GRCh38
• Cytoband: 12q24.13

Target Gene Details

• Entrez Gene ID: 4938
• Gene Name: 2'-5'-oligoadenylate synthetase 1
• Gene Aliases: E18/E16, IFI-4, OIAS, OIASI
• Location: Chr.12:112906777-112932190 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OAS1	NM_001032409.2			NP_001027581.1
	NM_001320151.1			NP_001307080.1
	NM_016816.3	6	1400	NP_058132.2
	XM_006719434.1	6	2019	XP_006719497.1
	XM_011538413.1			XP_011536715.1
	XM_017019361.1	6	1203	XP_016874850.1
	XM_017019362.1	6	1052	XP_016874851.1
	AA085948.1
	AJ629455.1			CAF33358.1
	AK225384.1	6	1200
	AY730627.1	6	1145	AAW63049.1
	AY730628.1			AAW63050.1
	BF055326.1	1	431
	DQ823040.1
	DQ914956.1
	X02661.1	3	447	CAA26497.1
	X02875.1	3	270	CAA26634.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832515	Chr.12:112778024 - 112926931 on Build GRCh38	Gain	OAS1 RPH3A
nsv1047747	Chr.12:112917435 - 113003116 on Build GRCh38	Gain	OAS3 OAS1 OAS2
nsv1042636	Chr.12:112627854 - 113014974 on Build GRCh38	Gain	OAS3 OAS1 MIR1302-1 RPH3A OAS2
nsv832516	Chr.12:112883300 - 113040797 on Build GRCh38	Gain	OAS3 OAS1 RPH3A OAS2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

nucleotidyltransferase

Gene Ontology Categories:

Process(es)

glucose metabolic process
response to virus
glucose homeostasis
negative regulation of viral genome replication
defense response to virus
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway

Function(s)

2'-5'-oligoadenylate synthetase activity
double-stranded RNA binding
protein binding
ATP binding
metal ion binding