Hs00882872_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155253 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	GFOD2 DUS2 FAM65A KCTD19 TPPP3 PSMB10 EXOC3L1 THAP11 DPEP3 E2F4 FBXL8 AGRP HSF4 EDC4 SLC9A5 FHOD1 LCAT TSNAXIP1 CTRL LOC105369155 TMEM208 NOL3 ELMO3 NUTF2 LRRC36 PARD6A MIR328 PLEKHG4 CTCF DPEP2 CARMIL2 TRADD C16orf86 LRRC29 LOC107984813 PSKH1 ZDHHC1 SLC12A4 ENKD1 ATP6V0D1 KIAA0895L HSD11B2 ACD DDX28 LOC100131303 CENPT NRN1L RANBP10 LOC100505942
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	SLC9A5 MIR328 KIAA0895L FHOD1 PLEKHG4 EXOC3L1 C16orf70 E2F4 FBXL8 TRADD LOC105369155 TMEM208 B3GNT9 LRRC29 NOL3 HSF4 ELMO3
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	MIR328 KIAA0895L FHOD1 EXOC3L1 C16orf70 E2F4 FBXL8 TRADD LOC105369155 TMEM208 B3GNT9 LRRC29 NOL3 HSF4 ELMO3
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	GFOD2 DUS2 FAM65A KCTD19 TPPP3 PSMB10 EXOC3L1 THAP11 DPEP3 E2F4 FBXL8 AGRP HSF4 EDC4 SLC9A5 FHOD1 LCAT TSNAXIP1 CTRL LOC105369155 TMEM208 B3GNT9 NOL3 ELMO3 NUTF2 LRRC36 PARD6A MIR328 PLEKHG4 CTCF DPEP2 CARMIL2 TRADD C16orf86 LRRC29 LOC107984813 PSKH1 ZDHHC1 SLC12A4 ENKD1 ATP6V0D1 KIAA0895L HSD11B2 ACD DDX28 LOC100131303 CENPT C16orf70 NRN1L RANBP10 LOC100505942

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding