Hs00912445_cn

• Gene Symbol: AGXT
• Assay Reference Genome Location: Chr.2:240868765 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 189
• Gene Name: alanine-glyoxylate aminotransferase
• Gene Aliases: AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6
• Location: Chr.2:240868745-240879119 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGXT	NM_000030.2			NP_000021.1
	BC132819.1
	D13368.1			BAA02632.1
	X53414.1			CAA37493.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv584861	Chr.2:240810727 - 241018260 on Build GRCh38	Gain	CROCC2 LOC200772 KIF1A C2orf54 SNED1 AGXT
nsv955294	Chr.2:240710484 - 240925283 on Build GRCh38	Deletion	CROCC2 KIF1A C2orf54 AGXT
nsv470531	Chr.2:240684476 - 240928657 on Build GRCh38	Loss	AQP12A LOC285191 AQP12B CROCC2 KIF1A C2orf54 AGXT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transaminase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
glyoxylate catabolic process
proteasomal protein catabolic process
glycine biosynthetic process, by transamination of glyoxylate
L-cysteine catabolic process
L-alanine catabolic process
pyruvate biosynthetic process
glyoxylate metabolic process
oxalic acid secretion
response to glucocorticoid
response to cAMP

Function(s)

serine-pyruvate transaminase activity
receptor binding
protein binding
alanine-glyoxylate transaminase activity
transaminase activity
amino acid binding
pyridoxal phosphate binding
protein homodimerization activity
protein self-association