Hs00941795_cn

• Gene Symbol: RASGRF1
• Assay Reference Genome Location: Chr.15:78961986 on build GRCh38
• Cytoband: 15q25.1

Target Gene Details

• Entrez Gene ID: 5923
• Gene Name: Ras protein specific guanine nucleotide releasing factor 1
• Gene Aliases: CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
• Location: Chr.15:78959947-79090873 on Build GRCh38
• Assay Gene Location: Within Exon 30

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RASGRF1	NM_001145648.1	27	4307	NP_001139120.1
	NM_002891.4	28	4355	NP_002882.3
	NM_153815.2	14	2801	NP_722522.1
	XM_011521867.2	27	4137	XP_011520169.1
	XM_017022455.1	28	4246	XP_016877944.1
	XM_017022456.1	27	4216	XP_016877945.1
	XM_017022459.1	26	4098	XP_016877948.1
	AK226101.1
	L26584.1			AAA58417.1
	M91815.1
	S62035.1	14	2810	AAB26881.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv33573	Chr.15:78761142 - 79001539 on Build GRCh38	Gain+Loss	RASGRF1 CTSH MORF4L1 ADAMTS7

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
signal transduction
small GTPase mediated signal transduction
long-term memory
cell proliferation
neuron projection development
regulation of Rac protein signal transduction
regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of Ras protein signal transduction
positive regulation of Ras protein signal transduction
regulation of synaptic plasticity
regulation of neuronal synaptic plasticity
activation of GTPase activity
regulation of N-methyl-D-aspartate selective glutamate receptor activity

Function(s)

guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
glutamate receptor binding