Hs00957307_cn

• Gene Symbol: NKX3-2
• Assay Reference Genome Location: Chr.4:13541120 on build GRCh38
• Cytoband: 4p15.33

Target Gene Details

• Entrez Gene ID: 579
• Gene Name: NK3 homeobox 2
• Gene Aliases: BAPX1, NKX3.2, NKX3B, SMMD
• Location: Chr.4:13540830-13544490 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NKX3-2	NM_001189.3	2	1951	NP_001180.1
	AF009801.1	2	1875	AAB82783.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv593750	Chr.4:13259081 - 13726709 on Build GRCh38	Gain	RAB28 MIR5091 LINC01182 NKX3-2 BOD1L1 HSP90AB2P LINC01096 LINC01097
nsv1014473	Chr.4:11586127 - 13990352 on Build GRCh38	Gain	RAB28 MIR5091 LINC01182 NKX3-2 LOC101929019 BOD1L1 HSP90AB2P LINC01096 LINC01097

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
transcription from RNA polymerase II promoter
determination of left/right symmetry
pancreas development
negative regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of apoptotic process
spleen development
organ formation
skeletal system morphogenesis
embryonic skeletal system development
intestinal epithelial cell development

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding