Hs00967034_cn

• Gene Symbol: RASGRP3
• Assay Reference Genome Location: Chr.2:33436470 on build GRCh38
• Cytoband: 2p22.3

Target Gene Details

• Entrez Gene ID: 25780
• Gene Name: RAS guanyl releasing protein 3
• Gene Aliases: GRP3
• Location: Chr.2:33436348-33564731 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RASGRP3	NM_170672.2	1	122	NP_733772.1
	XM_011532746.2	1	98	XP_011531048.1
	XM_017003759.1	1	98	XP_016859248.1
	XM_017003762.1	1	123	XP_016859251.1
	AK125551.1	1	145
	AK292983.1	1	33
	BC027849.1	1	122	AAH27849.1
	DA439087.1	1	98

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762447	Chr.2:33418657 - 33449417 on Build GRCh38	Gain	RASGRP3
esv3590286	Chr.2:33415480 - 33446957 on Build GRCh38	Loss	RASGRP3 MIR4430
esv3891725	Chr.2:33412332 - 33479056 on Build GRCh38	Gain	RASGRP3 MIR4430

More Information

Additional Information:

For this assay, SNP(s) [rs111314950] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
small GTPase mediated signal transduction
Ras protein signal transduction
positive regulation of GTPase activity

Function(s)

signal transducer activity
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
GTPase activator activity
calcium ion binding
protein binding
Ras GTPase binding
kinase binding
diacylglycerol binding