Hs01000293_cn

• Gene Symbol: CTGF
• Assay Reference Genome Location: Chr.6:131951334 on build GRCh38
• Cytoband: 6q23.2

Target Gene Details

• Entrez Gene ID: 1490
• Gene Name: connective tissue growth factor
• Gene Aliases: CCN2, HCS24, IGFBP8, NOV2
• Location: Chr.6:131948176-131951378 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTGF	NM_001901.2			NP_001892.1
	AK092280.1
	AK125220.1
	AK290884.1
	AK315207.1
	BC087839.1			AAH87839.1
	DA552292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv7968	Chr.6:131596032 - 131999959 on Build GRCh38	Loss	OR2A4 ENPP1 ENPP3 CTGF CTAGE9 MED23 MIR548H5

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

cartilage condensation
ossification
angiogenesis
regulation of cell growth
tissue homeostasis
transcription initiation from RNA polymerase II promoter
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
epidermis development
response to wounding
response to glucose
organ senescence
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
lung development
regulation of chondrocyte differentiation
response to estradiol
positive regulation of collagen biosynthetic process
response to anoxia
intracellular signal transduction
chondrocyte proliferation
response to amino acid
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to peptide hormone
positive regulation of cell differentiation
positive regulation of JNK cascade
positive regulation of cell activation
response to mineralocorticoid
positive regulation of stress fiber assembly
cytosolic calcium ion transport
positive regulation of cardiac muscle contraction
negative regulation of cell death
extracellular matrix constituent secretion
positive regulation of G0 to G1 transition
positive regulation of ERK1 and ERK2 cascade
response to fatty acid
DNA biosynthetic process
reactive oxygen species metabolic process

Function(s)

fibronectin binding
integrin binding
protein binding
insulin-like growth factor binding
protein C-terminus binding
growth factor activity
heparin binding