Hs01051988_cn

• Gene Symbol: HMOX1
• Assay Reference Genome Location: Chr.22:35389875 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3162
• Gene Name: heme oxygenase 1
• Gene Aliases: HMOX1D, HO-1, HSP32, bK286B10
• Location: Chr.22:35381067-35394214 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HMOX1	NM_002133.2			NP_002124.1
	AK313120.1
	BC001491.2			AAH01491.1
	BT019785.1			AAV38588.1
	CR456505.1			CAG30391.1
	CR541945.1			CAG46743.1
	CR541968.1			CAG46766.1
	JF323038.1
	X06985.1			CAA30045.1

More Information

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

angiogenesis
endothelial cell proliferation
wound healing involved in inflammatory response
negative regulation of leukocyte migration
heme oxidation
cellular iron ion homeostasis
response to oxidative stress
small GTPase mediated signal transduction
excretion
regulation of blood pressure
cell death
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of muscle cell apoptotic process
smooth muscle hyperplasia
cellular response to nutrient
negative regulation of mast cell cytokine production
erythrocyte homeostasis
low-density lipoprotein particle clearance
regulation of transcription from RNA polymerase II promoter in response to iron
cellular response to heat
response to nicotine
intracellular signal transduction
heme catabolic process
response to hydrogen peroxide
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of mast cell degranulation
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron apoptotic process
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
response to estrogen
positive regulation of chemokine biosynthetic process
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
negative regulation of smooth muscle cell proliferation
regulation of sequence-specific DNA binding transcription factor activity
protein homooligomerization
iron ion homeostasis
cellular response to arsenic-containing substance
cellular response to cadmium ion
cellular response to hypoxia
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

heme oxygenase (decyclizing) activity
phospholipase D activity
signal transducer activity
protein binding
enzyme binding
heme binding
protein homodimerization activity
metal ion binding