Hs01057276_cn

• Gene Symbol: PARS2
• Assay Reference Genome Location: Chr.1:54757473 on build GRCh38
• Cytoband: 1p32.3

Target Gene Details

• Entrez Gene ID: 25973
• Gene Name: prolyl-tRNA synthetase 2, mitochondrial (putative)
• Gene Aliases: MT-PRORS, proRS
• Location: Chr.1:54756898-54764553 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PARS2	NM_152268.3	2	1811	NP_689481.2
	AK025585.1	1	1493	BAB15178.1
	AL117473.1	1	1492	CAB55948.1
	BC007956.2	1	1726	AAH07956.2
	BC011758.2	2	1772	AAH11758.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1004778	Chr.1:54635180 - 54764639 on Build GRCh38	Gain	PARS2 TTC4 MROH7-TTC4 MROH7
dgv166n100	Chr.1:54741809 - 54804866 on Build GRCh38	Gain	TTC22 PARS2 TTC4 MROH7-TTC4
nsv1000673	Chr.1:54630765 - 54818045 on Build GRCh38	Gain	TTC22 LEXM PARS2 TTC4 MROH7-TTC4 ACOT11 MROH7
nsv546266	Chr.1:54404143 - 54887697 on Build GRCh38	Gain	TTC22 LEXM FAM151A SSBP3 PARS2 TTC4 MROH7-TTC4 ACOT11 MROH7 DHCR24
nsv461594	Chr.1:54593622 - 54757517 on Build GRCh38	Gain	FAM151A PARS2 TTC4 MROH7-TTC4 ACOT11 MROH7
dgv38e212	Chr.1:54627539 - 54817638 on Build GRCh38	Gain	TTC22 LEXM PARS2 TTC4 MROH7-TTC4 ACOT11 MROH7
nsv817614	Chr.1:54580862 - 55735351 on Build GRCh38	Gain	FAM151A PCSK9 MROH7-TTC4 MROH7 DHCR24 TTC22 BSND LEXM PARS2 TTC4 TMEM61 MIR4422 LOC100507634 ACOT11 USP24

More Information

Additional Information:

For this assay, SNP(s) [rs74946945] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

prolyl-tRNA aminoacylation

Function(s)

RNA binding
proline-tRNA ligase activity
ATP binding