Hs01059547_cn

• Gene Symbol: PRKAR2A
• Assay Reference Genome Location: Chr.3:48751029 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 5576
• Gene Name: protein kinase cAMP-dependent type II regulatory subunit alpha
• Gene Aliases: PKR2, PRKAR2
• Location: Chr.3:48744601-48847850 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKAR2A	NM_001321982.1			NP_001308911.1
	NM_001321983.1	10	1959	NP_001308912.1
	NM_004157.3	11	2025	NP_004148.1
	XM_011533942.2			XP_011532244.1
	XM_017006815.1			XP_016862304.1
	XM_017006816.1			XP_016862305.1
	AK023535.1	1	209
	AK293042.1
	BC002763.2	10	1937	AAH02763.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508918	Chr.3:48696212 - 48784507 on Build GRCh38	Insertion	PRKAR2A IP6K2
nsv590247	Chr.3:48624552 - 48764496 on Build GRCh38	Loss	CELSR3 NCKIPSD PRKAR2A CELSR3-AS1 MIR4793 MIR6824 SLC26A6 IP6K2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator, kinase modulator

Gene Ontology Categories:

Process(es)

renal water homeostasis
blood coagulation
activation of protein kinase A activity
intracellular signal transduction
cellular response to glucagon stimulus
negative regulation of cAMP-dependent protein kinase activity

Function(s)

cAMP-dependent protein kinase inhibitor activity
protein binding
cAMP-dependent protein kinase regulator activity
cAMP binding
ubiquitin protein ligase binding
protein kinase A catalytic subunit binding