Hs01063153_cn

• Gene Symbol: GRM6
• Assay Reference Genome Location: Chr.5:178980053 on build GRCh38
• Cytoband: 5q35.3

Target Gene Details

• Entrez Gene ID: 2916
• Gene Name: glutamate metabotropic receptor 6
• Gene Aliases: CSNB1B, GPRC1F, MGLUR6, mGlu6
• Location: Chr.5:178978327-178995123 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRM6	NM_000843.3	10	4417	NP_000834.2
	BX647168.1	2	2961	CAI46028.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv600489	Chr.5:178941095 - 179003374 on Build GRCh38	Loss	ZNF454 GRM6
nsv600490	Chr.5:178978250 - 179003374 on Build GRCh38	Loss	GRM6

More Information

Additional Information:

For this assay, SNP(s) [rs76846625] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
detection of visible light
detection of light stimulus involved in visual perception
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import

Function(s)

group III metabotropic glutamate receptor activity
G-protein coupled receptor activity
protein binding
glutamate receptor activity
protein homodimerization activity