Hs01072547_cn

• Gene Symbol: LILRB5
• Assay Reference Genome Location: Chr.19:54257283 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 10990
• Gene Name: leukocyte immunoglobulin like receptor B5
• Gene Aliases: CD85C, LIR-8, LIR8
• Location: Chr.19:54250405-54257308 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LILRB5	NM_001081442.2			NP_001074911.1
	NM_001081443.2			NP_001074912.1
	NM_001304457.1			NP_001291386.1
	NM_006840.4			NP_006831.1
	XM_011526359.2			XP_011524661.1
	XM_011526360.2			XP_011524662.1
	XM_011526361.2			XP_011524663.1
	XM_011526362.2			XP_011524664.1
	AF025534.1			AAB87668.1
	AK057072.1			BAB71361.1
	AK090399.1			BAC03380.1
	AK092867.1
	AK096122.1
	AK223296.1			BAD97016.1
	AK290845.1
	AK301112.1
	AK301338.1
	BC025704.1			AAH25704.1
	DC320482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2718863	Chr.19:54255259 - 54278883 on Build GRCh38	Deletion	LILRB5 LILRB2
nsv528370	Chr.19:54247206 - 54284902 on Build GRCh38	Loss	MIR4752 LILRB5 LILRB2
dgv3658n100	Chr.19:54218406 - 54270335 on Build GRCh38	Gain+Loss	LILRB5 LILRB3 LILRA6
nsv2548	Chr.19:54239379 - 54261184 on Build GRCh38	Insertion	LILRB5 LILRA6
dgv3656n100	Chr.19:54213432 - 54270335 on Build GRCh38	Gain	LILRB5 LILRB3 LILRA6
dgv3654n100	Chr.19:54212959 - 54303818 on Build GRCh38	Gain	MIR4752 LILRB5 LILRB2 LILRB3 LILRA6
esv2718860	Chr.19:54223005 - 54312746 on Build GRCh38	Deletion	MIR4752 LILRB5 LILRB2 LILRB3 LILRA6 LILRA5
nsv2546	Chr.19:54182614 - 54270671 on Build GRCh38	Deletion	LILRB5 LILRB3 RPS9 LILRA6 TSEN34 MBOAT7
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	ZNF525 MIR527 MIR525 MIR518A1 MIR518C LOC105372457 PRPF31 MIR935 MIR512-2 VN1R4 MIR519D MIR518B LILRA5 TPM3P9 MIR4752 MIR518D PRKCG MIR512-1 ZNF331 MIR517C MIR518A2 ZNF818P MIR526A2 MIR373 MIR517A MBOAT7 MIR520B MIR519A1 MYADM CACNG8 MIR515-1 CACNG6 MIR372 CNOT3 ZNF665 MIR518F MIR519A2 MIR518E MIR519B LILRB5 MIR516B2 ZNF813 MIR520D MIR371A BIRC8 NDUFA3 MIR524 MIR520A CACNG7 MIR523 DPRX MIR515-2 VN1R2 MIR371B TMC4 TARM1 LILRB2 ZNF677 MIR526A1 ZNF765 MIR517B MIR520C LILRA6 MIR1283-1 TSEN34 MIR520H MIR522 MIR520F MIR520E MIR498 LILRB3 MIR1323 MIR526B MIR519E FAM90A27P MIR516A2 MIR1283-2 MIR516B1 MIR519C OSCAR RPS9 ZNF845 VSTM1 MIR520G ZNF761 MIR516A1 TFPT LENG1 NLRP12 MIR521-1 MIR521-2 LOC284379
dgv3661n100	Chr.19:54249470 - 54336316 on Build GRCh38	Gain+Loss	MIR4752 LILRB5 LILRA4 LILRB2 LILRA5
nsv510774	Chr.19:54158011 - 54269511 on Build GRCh38	Deletion	LILRB5 TMC4 LILRB3 LENG1 RPS9 LILRA6 TSEN34 MBOAT7
dgv3657n100	Chr.19:54215071 - 54282373 on Build GRCh38	Gain	MIR4752 LILRB5 LILRB2 LILRB3 LILRA6
esv2758771	Chr.19:54163847 - 54954956 on Build GRCh38	Gain+Loss	KIR3DL1 TMC4 LILRB2 KIR2DL4 NLRP7 KIR3DL3 KIR3DL2 LILRA6 TSEN34 LILRA5 LILRB1 MIR4752 FCAR LOC102724300 NCR1 LILRB3 LENG8-AS1 MBOAT7 MIR8061 LENG9 LOC101928804 LILRA4 CDC42EP5 LILRA2 KIR3DX1 LILRP2 RPS9 LENG8 TTYH1 KIR2DL3 LAIR1 LAIR2 LILRB5 LILRA1 LILRB4 KIR2DL1 KIR2DS4
dgv1074e212	Chr.19:54218859 - 54292176 on Build GRCh38	Gain	MIR4752 LILRB5 LILRB2 LILRB3 LILRA6
nsv580227	Chr.19:54242679 - 54265351 on Build GRCh38	Loss	LILRB5 LILRA6
esv1003658	Chr.19:54215069 - 54257872 on Build GRCh38	Gain	LILRB5 LILRB3 LILRA6
esv2763032	Chr.19:54212971 - 54336316 on Build GRCh38	Gain+Loss	MIR4752 LILRB5 LILRA4 LILRB2 LILRB3 LILRA6 LILRA5
dgv3660n100	Chr.19:54226329 - 54340836 on Build GRCh38	Gain	MIR4752 LILRB5 LILRA4 LILRB2 LILRA6 LILRA5
nsv435704	Chr.19:54248618 - 54274775 on Build GRCh38	Deletion	LILRB5 LILRB2
esv3574853	Chr.19:54226365 - 54326343 on Build GRCh38	Gain	MIR4752 LILRB5 LILRB2 LILRA6 LILRA5
nsv183	Chr.19:54212629 - 54265267 on Build GRCh38	Deletion	LILRB5 LILRB3 LILRA6
dgv6549n54	Chr.19:54219677 - 54336316 on Build GRCh38	Gain	MIR4752 LILRB5 LILRA4 LILRB2 LILRB3 LILRA6 LILRA5
nsv580192	Chr.19:54227805 - 54258559 on Build GRCh38	Gain+Loss	LILRB5 LILRA6

More Information

Additional Information:

For this assay, SNP(s) [rs190489750] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

adaptive immune response
defense response
cell surface receptor signaling pathway

Function(s)

transmembrane signaling receptor activity