Hs01094348_cn

• Gene Symbol: UBE2C
• Assay Reference Genome Location: Chr.20:45815768 on build GRCh38
• Cytoband: 20q13.12

Target Gene Details

• Entrez Gene ID: 11065
• Gene Name: ubiquitin conjugating enzyme E2 C
• Gene Aliases: UBCH10, dJ447F3.2
• Location: Chr.20:45812576-45816957 on Build GRCh38
• Assay Gene Location: Overlaps Exon 6 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2C	NM_001281741.1			NP_001268670.1
	NM_001281742.1			NP_001268671.1
	NM_007019.3			NP_008950.1
	NM_181799.2			NP_861515.1
	NM_181800.2			NP_861516.1
	NM_181801.3			NP_861517.1
	NR_104036.1
	NR_104037.1
	AK311949.1
	BC007656.2			AAH07656.1
	BC016292.1			AAH16292.1
	BC050736.1			AAH50736.1
	BI858659.1
	BM556795.1
	BP227692.1
	BT007300.1			AAP35964.1
	BT020165.1			AAV38967.1
	BT020166.1			AAV38968.1
	BU169315.1
	BU171488.1
	BU844974.1
	CB143441.1
	CK904708.1
	CN354813.1
	CN354815.1
	CR456988.1			CAG33269.1
	DB062573.1
	U73379.1			AAB53362.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv965879	Chr.20:45815184 - 45815989 on Build GRCh38	Duplication	UBE2C
nsv833990	Chr.20:45771510 - 45946844 on Build GRCh38	Loss	UBE2C LOC107985388 TNNC2 SNX21 PLTP DNTTIP1 NEURL2 ZSWIM3 WFDC3 SPATA25 PCIF1 ZSWIM1 ACOT8 CTSA
nsv586132	Chr.20:45785138 - 45842587 on Build GRCh38	Loss	UBE2C DNTTIP1 TNNC2 WFDC3 SNX21 ACOT8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation
exit from mitosis
free ubiquitin chain polymerization
protein ubiquitination
regulation of mitotic metaphase/anaphase transition
anaphase-promoting complex-dependent catabolic process
positive regulation of exit from mitosis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K48-linked ubiquitination
protein K11-linked ubiquitination
positive regulation of ubiquitin protein ligase activity

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
ubiquitin protein ligase activity
ubiquitin conjugating enzyme activity