Hs01137741_cn

• Gene Symbol: DAGLB
• Assay Reference Genome Location: Chr.7:6410389 on build GRCh38
• Cytoband: 7p22.1

Target Gene Details

• Entrez Gene ID: 221955
• Gene Name: diacylglycerol lipase beta
• Gene Aliases: DAGLBETA, KCCR13L
• Location: Chr.7:6409116-6448012 on Build GRCh38
• Assay Gene Location: Overlaps Intron 13 - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DAGLB	NM_001142936.1			NP_001136408.1
	NM_139179.3			NP_631918.3
	AF450090.1			AAL47020.1
	AK074210.1			BAB85017.1
	AK074584.1			BAC11073.1
	AK074744.1			BAC11175.1
	AK075128.1			BAC11420.1
	AK090943.1
	AK091228.1
	AK093958.1			BAC04258.1
	AK122748.1
	AK298910.1
	AK298955.1
	AK301087.1
	BC027603.1			AAH27603.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1020236	Chr.7:6209299 - 6650746 on Build GRCh38	Gain	DAGLB RAC1 C7orf26 ZNF853 CYTH3 GRID2IP ZDHHC4 ZNF316 FAM220A KDELR2
nsv606000	Chr.7:6406396 - 6437371 on Build GRCh38	Loss	DAGLB
nsv436904	Chr.7:5035574 - 6713282 on Build GRCh38	Insertion	DAGLB RAC1 LOC100129484 C7orf26 CCZ1 RNF216-IT1 FSCN1 LOC107986762 AIMP2 FAM220A ZNF12 FBXL18 ZNF815P ZNF853 RSPH10B LOC221946 ZNF316 KDELR2 LOC100419773 OCM RBAK-RBAKDN ZNF890P RBAK ZDHHC4 EIF2AK1 TNRC18 USP42 WIPI2 CYTH3 GRID2IP RBAKDN PMS2 MIR6874 SLC29A4 ACTB MIR589 RNF216 ANKRD61
nsv605999	Chr.7:6357088 - 6433250 on Build GRCh38	Loss	DAGLB RAC1

More Information

Additional Information:

For this assay, SNP(s) [rs73676731] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lipase

Gene Ontology Categories:

Process(es)

neuroblast proliferation
lipid catabolic process
arachidonic acid metabolic process
neurotransmitter biosynthetic process

Function(s)

metal ion binding
acylglycerol lipase activity