Hs01194123_cn

• Gene Symbol: TRIM28
• Assay Reference Genome Location: Chr.19:58549124 on build GRCh38
• Cytoband: 19q13.43

Target Gene Details

• Entrez Gene ID: 10155
• Gene Name: tripartite motif containing 28
• Gene Aliases: KAP1, PPP1R157, RNF96, TF1B, TIF1B
• Location: Chr.19:58544469-58550715 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM28	NM_005762.2	12	1835	NP_005753.1
	AK131063.1	5	423
	AK225760.1	12	1835
	AK313478.1	12	1552
	BC004978.1	12	1835	AAH04978.1
	BC007390.2	1	152	AAH07390.2
	BC052986.2	10	1586	AAH52986.1
	U31657.1	1	91	AAA74954.1
	U78773.1	12	1646	AAB37341.1
	U95040.1	12	1802	AAB51517.1
	X97548.1	12	1907	CAA66150.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057206	Chr.19:58546716 - 58586475 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M CENPBD1P1 TRIM28 MZF1 MZF1-AS1
dgv3687n100	Chr.19:58473466 - 58586475 on Build GRCh38	Gain	ZNF446 MIR6807 CHMP2A ZNF324 UBE2M SLC27A5 ZBTB45 CENPBD1P1 TRIM28 MZF1 MZF1-AS1
nsv515731	Chr.19:58320453 - 58576112 on Build GRCh38	Gain+Loss	ZNF446 ZNF132 LOC105372483 ZNF584 SLC27A5 ZNF837 MIR4754 ZNF324B ZNF324 CENPBD1P1 RPS5 A1BG-AS1 MZF1 MIR6807 LOC100419840 ZSCAN22 CHMP2A UBE2M TRIM28 ZNF497 MIR6806 LOC100506634 RNF225 ZBTB45 A1BG MZF1-AS1
nsv952156	Chr.19:58466134 - 58600733 on Build GRCh38	Deletion	ZNF446 MIR6807 CHMP2A ZNF324 UBE2M SLC27A5 ZBTB45 CENPBD1P1 TRIM28 MZF1 MZF1-AS1
nsv1160670	Chr.19:58433008 - 58586487 on Build GRCh38	Deletion	ZNF446 MIR6807 CHMP2A ZNF132 UBE2M SLC27A5 TRIM28 ZNF324B ZNF324 ZBTB45 CENPBD1P1 MZF1 MZF1-AS1
nsv828657	Chr.19:58483484 - 58585740 on Build GRCh38	Gain	ZNF446 MIR6807 CHMP2A UBE2M SLC27A5 ZBTB45 CENPBD1P1 TRIM28 MZF1 MZF1-AS1
dgv3688n100	Chr.19:58506055 - 58586475 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M SLC27A5 ZBTB45 CENPBD1P1 TRIM28 MZF1 MZF1-AS1
nsv1057077	Chr.19:58411953 - 58586475 on Build GRCh38	Gain	ZNF446 MIR6807 CHMP2A ZNF132 UBE2M ZNF584 SLC27A5 TRIM28 ZNF324B ZNF324 ZBTB45 CENPBD1P1 MZF1 MZF1-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
epithelial to mesenchymal transition
DNA repair
transcription initiation from RNA polymerase II promoter
Ras protein signal transduction
embryo implantation
protein ubiquitination
covalent chromatin modification
protein sumoylation
positive regulation of transcription factor import into nucleus
DNA methylation involved in embryo development
innate immune response
positive regulation of DNA repair
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
protein oligomerization
convergent extension involved in axis elongation
embryonic placenta morphogenesis
positive regulation of methylation-dependent chromatin silencing
negative regulation of DNA demethylation
negative regulation of viral release from host cell
regulation of genetic imprinting

Function(s)

RNA polymerase II transcription coactivator activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein kinase activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
Krueppel-associated box domain binding
sequence-specific DNA binding
poly(A) RNA binding
chromo shadow domain binding
promoter-specific chromatin binding