Hs01227928_cn

• Gene Symbol: DDIT4
• Assay Reference Genome Location: Chr.10:72274386 on build GRCh38
• Cytoband: 10q22.1

Target Gene Details

• Entrez Gene ID: 54541
• Gene Name: DNA damage inducible transcript 4
• Gene Aliases: Dig2, REDD-1, REDD1
• Location: Chr.10:72273919-72276039 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DDIT4	NM_019058.2	2	372	NP_061931.1
	AF335324.1	2	388	AAL38424.1
	AK000507.1	2	367	BAA91214.1
	AL136668.1	2	371	CAB66603.1
	AY090097.1	2	288	AAM10442.1
	BC000708.1	2	278	AAH00708.1
	BC007714.1	2	360	AAH07714.1
	BC015236.1	2	346	AAH15236.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2761604	Chr.10:72262756 - 72287410 on Build GRCh38	Loss	DDIT4
nsv551514	Chr.10:72243964 - 72286159 on Build GRCh38	Loss	DDIT4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
neuron migration
brain development
cell proliferation
negative regulation of peptidyl-threonine phosphorylation
neuron differentiation
negative regulation of TOR signaling
negative regulation of peptidyl-serine phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
protein complex disassembly
negative regulation of glycolytic process
neurotrophin TRK receptor signaling pathway
defense response to virus
reactive oxygen species metabolic process
positive regulation of neuron death
negative regulation of intracellular signal transduction

Function(s)

14-3-3 protein binding